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 DiscoverX c-Kit (V654A), active 14-733 14-733|产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
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    DiscoverX c-Kit (V654A), active 14-733
    品牌:Eurofins DiscoverX
    货号:14-733
    规格:14-733
    货期:DiscoverX

    品牌:DiscoverX 品名:c-Kit (V654A), active 货号:14-733 规格:10 µg

    商品详情 参考文献 相关资料
    品牌:DiscoverX
    品名:c-Kit (V654A), active
    货号:14-733  
    规格:10 µg

    简要说明:

    c-Kit (V654A), active

    N-terminal GST-tagged recombinant, human c-Kit amino acids 544 - end containing the V654A mutation. Co-ordinates encompass the cytoplasmic domain (544-976) according in Swiss Prot P10721. V654A is an acquired resistance mutation which has been found in patients with gastrointestinal stromal tumours (GISTs) undergoing treatment with Imatinib. The V654A mutation is strongly correlated with imatinib resistance and rapid progession of GISTs. (Chen LL et al., Cancer Research, (2004); 64:5913-5919).


    产品介绍:

    Target
    c-Kit
    Expression System
    Expressed by baculovirus in Sf21 insect cells
    Application
    Kinase Assay
    Molecular Weight
    76.7 kDa
    Accession Number
    NM_000222.2; NM_001093772.1
    Species
    Human
    Tag
    GST
    Purity
    Purity 99% by SDS-PAGE and Coomassie blue staining.
    Purification Method
    Glutathione agarose affinity chromatography
    Storage
    6 months at -70°C
    Bulk Sizes
    Inquire
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