Catalogue number
PRO-2062
Synonyms
Ankyrin Repeat, Family A (RFXANK-Like), 2, ANKRA,
RFXANK-Like Protein 2, Ankyrin Repeat Family A Protein 2, ANKRA2.
Introduction
Ankyrin Repeat Family A2, also known as ANKRA2 contains 5 ANK repeats.
ANKRA2 assist endocytosis by linking megalin to components of the cytoskeleton
or endocytic machinery.
Description
ANKRA2 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 336 amino acids (1-313a.a) and
having a molecular mass of 36.7kDa.
ANKRA2 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
ANKRA2 protein solution (0.25 mg/ml) containing 20mM
Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater
than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMDTSTNL DIGAQLIVEE CPSTYSLTGM PDIKIEHPLD PNSEEGSAQG
VAMGMKFILP NRFDMNVCSR FVKSLNEEDS KNIQDQVNSD LEVASVLFKA ECNIHTSPSP GIQVRHVYTP
STTKHFSPIK QSTTLTNKHR GNEVSTTPLL ANSLSVHQLA
AQGEMLYLAT RIEQENVINH TDEEGFTPLM WAAAHGQIAV VEFLLQNGAD
PQLLGKGRES ALSLACSKGY TDIVKMLLDC GVDVNEYDWN GGTPLLYAVH GNHVKCVKML LESGADPTIE
TDSGYNSMDL AVALGYRSVQ QVIESHLLKL LQNIKE.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
