Catalogue number
ENZ-554
Synonyms
GNP1, GNPDA, GNPI, GPI, HLN, Oscillin.
Introduction
GNPDA1, catalyzes the conversion of glucosamine-6-phosphate to fructose-6-phosphate, a reaction that under physiological conditions proceeds to the formation of fructose-6-phosphate. GNPDA1 is widely expressed with highest expression in testes, ovary and heart. GNPDA1 triggers calcium oscillations in mammalian eggs. These oscillations are as the necessary trigger for egg activation and early development of the embryo.
Description
GNPDA1 Recombinant Human produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 309 amino acids (1-289) and having a molecular mass of 34.8 kDa.
GNPDA1 is fused to a 20 amino macid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
1 mg/ml solution containing 20mM Tris Hcl buffer pH-8, 1mM DTT, 50mM NaCl and 20% glycerol.
Stability
GNPDA1 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C.
Please prevent freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MKLIILEHYS QASEWAAKYI RNRIIQFNPG PEKYFTLGLP TGSTPLGCYK KLIEYYKNGD LSFKYVKTFN
MDEYVGLPRD HPESYHSFMW NNFFKHIDIH PENTHILDGN AVDLQAECDA FEEKIKAAGG IELFVGGIGP DGHIAFNEPG SSLVSRTRVK
TLAMDTILAN ARFFDGELTK VPTMALTVGV GTVMDAREVM ILITGAHKAF ALYKAIEEGV NHMWTVSAFQ QHPRTVFVCD EDATLELKVK
TVKYFKGLML VHNKLVDPLY SIKEKETEKS QSSKKPYSD.
Safety Data Sheet
Usage
Prospecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
