Catalogue number
PRO-2288
Synonyms
CUB and Zona Pellucida-Like Domains 1, CUB and ZP Domain-Containing Protein 1, Transmembrane Protein UO-44, Estrogen Regulated Gene 1, ERG-1, UO-44, CUZD1.
Introduction
CUB and Zona Pellucida-Like Domains 1 (CUZD1) antiserum inhibits cell attachment and proliferation of ovarian cancer cells therefore may be involved in these processes. In addition, CUZD1 may also have a role in the uterus during late pregnancy and/or in trypsin activation in pancreatic acinar cells.
Description
CUZD1 Human Recombinant produced in HEK cells is a single, glycosylated, polypeptide chain (Glu25-Ser568) containing a total of 554 amino acids, having a calculated molecular mass of 62.2kDa and fused to a 10 aa His tag at C-Terminus.
Source
HEK 293.
Physical Appearance
Filtered White lyophilized (freeze-dried) powder.
Formulation
CUZD1 was filtered (0.4µm) and lyophilized in phosphate buffered saline and 5% (w/v) trehalose.
Solubility
It is recommended to add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. CUZD1 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Stability
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Amino acid sequence
EAEGNASCTV SLGGANMAET HKAMILQLNP SENCTWTIER PENKSIRIIF SYVQLDPDGS CESENIKVFD GTSSNGPLLG QVCSKNDYVP VFESSSSTLT FQIVTDSARI QRTVFVFYYF FSPNISIPNC GGYLDTLEGS FTSPNYPKPH PELAYCVWHI QVEKDYKIKL NFKEIFLEID KQCKFDFLAI YDGPSTNSGL IGQVCGRVTP TFESSSNSLT VVLSTDYANS YRGFSASYTS IYAENINTTS LTCSSDRMRV IISKSYLEAF NSNGNNLQLK DPTCRPKLSN VVEFSVPLNG CGTIRKVEDQ SITYTNIITF SASSTSEVIT RQKQLQIIVK CEMGHNSTVE IIYITEDDVI QSQNALGKYN TSMALFESNS FEKTILESPY YVDLNQTLFV QVSLHTSDPN LVVFLDTCRA SPTSDFASPT YDLIKSGCSR DETCKVYPLF GHYGRFQFNA FKFLRSMSSV YLQCKVLICD SSDHQSRCNQ GCVSRSKRDI SSYKWKTDSI IGPIRLKRDR SASGNSGFQH ETHAEETPNQ PFNS HHHHHH HHHH.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
