Catalogue number
CKI-273
Synonyms
Creatine kinase M-type, EC 2.7.3.2, Creatine kinase M chain, M-CK, CKM, CKMM.
Introduction
The three isoenzymes (MM, MB, and BB) are found in muscle, cardiac and brain tissues. These recombinant proteins are ideal for calibrating diagnostic instruments and researching neuromuscular diseases. Creatine Kinases can be used for indications in many neuromuscular applications. These disorders include cardiac disease, mitochondrial disorders, inflammatory myopathies, myasthenia, polymyositis, McArdle''s disease, NMJ disorders, muscular dystrophy, ALS, hypo and hyperthyroid disorders, central core disease, acid maltase deficiency, myoglobinuria, rhabdomyolysis, motor neuron diseases, rheumatic diseases, and other that create elevated or reduced levels of Creatine Kinases.
Description
Human CKM produced in Human Cardiac Tissues having a molecular mass of 82 kDa and PI 5.0-7.5. It’s the skeletal muscle specific creatine kinase and is elevated in case of strenuous exercise and in degenerative muscle disease.
Source
Human Cardiac Tissues
Physical Appearance
Sterile Filtered clear solution.
Formulation
The CKM protein solution is in 50mM Tris and 2mM DTT, pH 7.5 containing 50% Glycerol.
Stability
CKM although stable at 14°C for 1 week, should be stored at 2°-8°C.
Purity
Greater than 50.0%.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
