Catalogue number
PRO-2029
Synonyms
C1q and Tumor Necrosis Factor Related Protein 4, CTRP4, Complement-C1q Tumor Necrosis Factor-Related Protein 4, Complement C1q Tumor Necrosis Factor-Related Protein 4, ZACRP4, C1QTNF4.
Introduction
C1QTNF4 serves as a pro-inflammatory cytokine, which induces the
activation of NF-kappa-B signaling pathway and up-regulates IL6 production.
Description
C1QTNF4 Human Recombinant produced in HEK cells is a single, glycosylated, polypeptide chain (Leu17-Leu329) containing a total of 319 amino acids, having a calculated molecular mass of 34.5kDa and fused to a 6 aa His tag at C-Terminus.
Source
Escherichia Coli.
Physical Appearance
Filtered colorless solution.
Formulation
C1QTNF4 filtered (0.4µm) solution at a concentration of 0.25mg/ml in phosphate buffered saline.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
LGPTPGPGSS ELRSAFSAAR TTPLEGTSEM AVTFDKVYVN IGGDFDVATG QFRCRVPGAY FFSFTAGKAP HKSLSVMLVR NRDEVQALAF DEQRRPGARR AASQSAMLQL DYGDTVWLRL HGAPQYALGA PGATFSGYLV YADADADAPA RGPPAPPEPR SAFSAARTRS LVGSDAGPGP RHQPLAFDTE FVNIGGDFDA AAGVFRCRLP GAYFFSFTLG KLPRKTLSVK LMKNRDEVQA MIYDDGASRR REMQSQSVML ALRRGDAVWL LSHDHDGYGA YSNHGKYITF SGFLVYPDLA PAAPPGLGAS ELL HHHHHH.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
