Catalogue number
CYT-796
Synonyms
CD116, CDw116, CSF2R, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4,
GMR-alpha, CD116 Antigen, CSF2RAX, CSF2RY, CSF2RAY, CSF2RX, Colony Stimulating
Factor 2 Receptor Alpha Subunit, GM-CSF Receptor Alpha Subunit, Granulocyte-Macrophage
Colony-Stimulating Factor Receptor Alpha Chain, Granulocyte-Macrophage
Colony-Stimulating Factor Receptor Subunit Alpha.
Introduction
GM-CSF
Receptor Alpha (CSF2RA) is the alpha subunit of the heterodimeric receptor for
colony stimulating factor 2, a cytokine which controls the production,
differentiation, and function of granulocytes and macrophages. CSFR2 is also a
member of the cytokine family of receptors. In addition, this gene is found in
the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple
transcript variants encoding various isoforms have been found for this gene, while
some of the isoforms being membrane-bound and others being soluble. Diseases
associated with CSF2RA include surfactant metabolism dysfunction, pulmonary 4,
and csf2ra-related pulmonary surfactant metabolism dysfunction.
Description
CSF2RA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 324 amino acids (20-320 a.a) and having a molecular mass of 37.2kDa.
CSF2RA is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
CSF2RA protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater
than 85.0% as determined by SDS-PAGE.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
