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 PURE - anti mouse CD152 - Clone UC10-4F10-11 |产品详情|进口橙子视频旧款采购网




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    PURE - anti mouse CD152 - Clone UC10-4F10-11
    品牌：Immunostep
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    PURE - anti mouse CD152 - Clone UC10-4F10-11
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    PURE - anti Mouse CD152 - UC10-4F10-11

    Reference Size Price Quantity Add to cart
    100,00 € tax excl.

    220,00 € tax excl.

    Product Description

    • UC10-4F10-11
    • Armenian Hamster IgG
    • Flow Cytometry
    • PURE
    • 0.5 mg/ml
    • Mouse CTLA-4 IgG2a Fusion
    • Mouse
    • The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
    • RUO
    • CD152, clone UC10-AF10-11, is a mAb intended for RUO in the identification/enumeration of lymph that express CD152. This reagent is effective for direct IF staining of mouse sample for FCM analysis using ≤1 μg/106 cells.
    • Liquid
    • Store in the dark at 2-8 °C
    Mouse PU-PP-B Vial View larger
    CD152 also known as, Cytotoxic T-lymph ocyte-associated antigen 4 (CTLA-4). CD152 is expressed on activated T lymph ocytes 2-3 days after stimulation through T cell receptor. CTLA-4 has significant similarity to CD28 in amino acid sequence, structure, and genomic organization. Furthermore, CD152 and CD28 share common B7 family counter-receptors. Unlike CD28, CD152 expression appears to be restricted to activated T cells and CD25+CD4+ regulatory T (Treg) cells. Whereas CD28 delivers a costimulatory signal required for T-cell activation, CTLA-4 is a negative regulator of cell-mediated immune responses. CD152 may play roles in induction and/or maintenance of immunological tolerance, regulation of protective immunity, and autoimmune responses, and regulation of some aspects of thymocyte maturation. This hamster mAb to a mouse leukocyte antigen does not cross-react with rat leucocytes.
    • Ctla4; CTLA-4; Cytotoxic T-lymph ocyte-associated protein 4; Ly-56
    • 12477
    • 33 kD
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