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 PE - anti human CD16 - Clone 3G8 |产品详情|进口橙子视频旧款采购网




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    PE - anti human CD16 - Clone 3G8
    品牌:Immunostep
    货号:
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    PE - anti human CD16 - Clone 3G8

    商品详情 参考文献 相关资料

    PE - anti Human CD16 - 3G8

    Reference Size Price Quantity Add to cart
    16PE2-100T 100 test
    230,00 € tax excl.

    Product Description

    • 3G8
    • IgG1
    • FCM
    • PE
    • Please refer to the Certificate of Analysis for the lot-specific concentration.
    • Human polymorphonuclear leukocytes
    • Human
    • The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
    • IVD-CE
    • Store in the dark at 2-8 °C
    CD16 View larger
    • CD16
    • CD16

    This antibody reacts with the CD16-antigen. CD16 exists as two distinct isoforms, FcγRIIIA and FcγRIIIB. In humans, FcγRIIIA is expressed as a polypeptide-anchored form on monocytes, macrophages, and lymphocytes such as NK cells. T and B cells do not express this Fc receptor. FcγRIIIB is also detected on neutrophils as a GPI-anchored form. Expression of CD16 on lymphocytes and monocytes is similar in non-human primates. Binding of IgG leads to activation of signal transduction pathways, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, cytokine release, and antigen presentation.

    • FCRIII, Fc-gamma receptor IIIb, CD16, FCG3, FCGR3, IGFR6
    • 50-65 kDa
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