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MMP25 Antibody abx002193|产品详情|进口橙子视频旧款采购网




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    MMP25 Antibody
    品牌:
    货号:abx002193
    规格:10 μl
    货期:

    MMP25 Antibody

    商品详情 参考文献 相关资料
    MMP25 Antibody is a Rabbit Polyclonal antibody against MMP25. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.

    Target Matrix Metalloproteinase 25 (MMP25)
    Reactivity Human
    Origin Human
    Host Rabbit
    Clonality Polyclonal
    Tested Applications WB, IHC
    Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
    Immunogen A synthetic peptide of human MMP25.
    Purification Affinity purified.
    Form Liquid
    Isotype IgG
    Conjugation Unconjugated
    Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
    Molecular Weight Calculated MW: 62 kDa
    Observed MW: 76 kDa
    Swiss Prot Q9NPA2
    GeneID 64386
    Gene Symbol MMP25
    Concentration 1.21 mg/ml
    Buffer PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
    Availability Shipped within 5-10 working days.
    Note This product is for research use only.
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