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 HDAC7 Antibody abx026075|产品详情|进口橙子视频旧款采购网




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    HDAC7 Antibody
    品牌:
    货号:abx026075
    规格:80 μl
    货期:

    HDAC7 Antibody

    商品详情 参考文献 相关资料
    Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the eta-amino groups of lysines located near the amino termini of core histone proteins (1). Eight members of HDAC family have been identified in the past several years (2, 3). These HDAC family members are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8, each of which contains a deacetylase domain exhibiting from 45 to 93% identity in amino acid sequence. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold larger than those of the class I members, and the deacetylase domains are present within the C-terminal regions, except that HDAC-6 contains two copies of the domain, one within each of the N-terminal and C-terminal regions. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns (3). These results suggested that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo.

    Target HDAC7
    Reactivity Human
    Host Rabbit
    Clonality Polyclonal
    Tested Applications WB
    Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
    Immunogen Human HDAC7.
    Purification Purified Rabbit Polyclonal Antibody.
    Isotype IgG
    Conjugation Unconjugated
    Specificity This HDAC7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 920-952 amino acids from the C-terminal region of human HDAC7.
    Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
    Swiss Prot Q8WUI4
    Buffer PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Availability Shipped within 5-10 working days.
    Note This product is for research use only.
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