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RNF2 Antibody is a Rabbit Polyclonal antibody against RNF2. Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

Target	RNF2
Reactivity	Human, Mouse, Rat
Origin	Human
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB, IHC, IP, ChIP
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IP: 1/50 - 1/200, ChIP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant protein of human RNF2.
Purification	Affinity purified.
Form	Liquid
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Calculated MW: 29 kDa/37 kDa Observed MW: 39 kDa
Swiss Prot	Q99496
GeneID	6045
Gene Symbol	RNF2
Concentration	> 1 mg/ml
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.