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This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain.The protein is an essential regulator of ventral neuroectodermal progenitor cell fate.The gene is involved in a chromosomal translocations t (14;21) (q11.2;q22) associated with T-cell acute lymphoblastic leukemia.Its chromosomal locations is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.Tissue specificity: Expressed in the brain, in oligodendrocytes.Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas.Expression in glioblastomas highly variable.

Target	OLIG2
Reactivity	Human, Mouse, Rat, Chicken
Host	Mouse
Clonality	Monoclonal
Tested Applications	ELISA, WB, IHC, IF/ICC
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Purified recombinant fragment of human OLIG2 expressed in E. coli.
Isotype	IgG1
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight	32 kDa
GeneID	10215 50913 304103 428612
Buffer	Ascitic fluid containing 0.03% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.