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H3 (pS28) Antibody is a Rabbit Polyclonal antibody against H3 (pS28). Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Target	H3 (pS28)
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Tested Applications	ELISA, WB
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Human H3 (phospho-Ser28).
Purification	Purified by Protein A chromatography, followed by peptide affinity purification.
Isotype	IgG
Conjugation	Unconjugated
Specificity	This antibody is generated from rabbits immunised with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S10 of human H3.
Storage	Store at 2-8 °C for up to 2 weeks. Aliquot and store at -20 °C for long-term storage. Avoid repeated freeze/thaw cycles.
Molecular Weight	15.4 kDa (calculated)
Swiss Prot	P68431
Buffer	PBS with 0.09% (W/V) sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.