橙子视频app安卓下载,91橙子视频,橙子视频旧款,橙子视频在线官网

SYK Antibody is a Rabbit Polyclonal antibody against SYK. Syk is a protein tyrosine kinase that plays an important role in intracellular signal transduction in hematopoietic cellsSyk interacts with immunoreceptor tyrosine-based activation motifs (ITAMs) located in the cytoplasmic domains of immune receptorsIt couples the activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including prolifeRation, differentiation, and phagocytosisThere is also evidence of a role for Syk in nonimmune cells, and investigators have indicated that Syk is a potential tumor suppressor in human breast carcinomasTyr323 is a negative regulatory phosphorylation site within the SH2-kinase linker region in SykPhosphorylation of Tyr323 provides a direct to the TKB domain of CblTyrosine 352 of Syk is involved in the association of PLC-γ1Tyrosines 525 and 526 are located in the activation loop of the Syk kinase domain, and phosphorylation of Tyr525/526 of human Syk (equivalent to the Tyr519/520 of mouse Syk) is essential for Syk function.

Target	SYK
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB, IHC
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant protein of human SYK.
Purification	Affinity purified.
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot	P43405
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.