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This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Target	SPI1
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Tested Applications	IF/ICC
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Human SPI1.
Purification	Peptide Affinity Purified Rabbit Polyclonal Antibody.
Isotype	IgG
Conjugation	Unconjugated
Specificity	This SPI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human SPI1.
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot	P17947
Gene Symbol	SPI1
Buffer	PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.