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Phospho-Catenin beta (Ser33) Antibody detects endogenous levels of Catenin beta only when phosphorylated at Serine 33. Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior.

Target	Catenin beta (pS33)
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Tested Applications	IHC
Recommended dilutions	IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	A synthesized peptide derived from human Catenin beta around the phosphorylation site of Serine 33.
Purification	Immunogen affinity purified.
Conjugation	Unconjugated
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot	P35222
Buffer	Rabbit IgG in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.