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 Recombinant Human TGF-α |产品详情|进口橙子视频旧款采购网




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    Recombinant Human TGF-α
    品牌:PeproTech
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    Recombinant Human TGF-α

    商品详情 参考文献 相关资料

    TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.

    Source: E.coli

    Synonyms: Transforming Growth Factor-α, Sacroma growth factor, TGF-type I, ETGF

    AA Sequence: VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA

    Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

    Biological Activity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.

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