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 Recombinant Guinea Pig TNF alpha IRKFAP0254|产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    Recombinant Guinea Pig TNF alpha
    品牌:Innovative Research
    货号:IRKFAP0254
    规格:5ug
    货期:

    Recombinant Guinea Pig TNF alpha

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    Product Description

    Recombinant Guinea Pig TNF alpha


    Recombinant Guinea Pig TNF alpha is primarily produced as a 212-amino acid-long type II transmembrane protein arranged in stable homotrimers. From this membrane-integrated form the soluble homotrimeric cytokine (sTNF) is released via proteolytic cleavage by the metalloprotease TNF alpha converting enzyme (TACE, also called ADAM17). The soluble 51 kDa trimeric sTNF tends to dissociate at concentrations below the nanomolar range, thereby losing its bioactivity. The secreted form of human TNF- takes on a triangular pyramid shape, and weighs around 17-kD. Both the secreted and the membrane bound forms are biologically active, although the specific functions of each is controversial. But, both forms do have overlapping and distinct biology activities.

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