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 Recombinant Feline IL-6 IRKFAP0232 |产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    Recombinant Feline IL-6
    品牌:Innovative Research
    货号:IRKFAP0232
    规格:5ug
    货期:

    Recombinant Feline IL-6

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    Product Description

    Recombinant Feline IL-6

    Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6 is also produced from muscle, and is elevated in response to muscle contraction. It is significantly elevated with exercise, and precedes the appearance of other cytokines in the circulation. Osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. The role of IL-6 as an anti-inflammatory cytokine is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10. The biological activity of recombinant feline IL-6 was measured in a cell proliferation assay using the mouse B9 cell line. The ED50 for this effect is typically 10-20 pg/mL. The biological activity was also measured in 7TD1 cells. The ED50 for this effect is typically 0.2-0.3 ng/mL.

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