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KLF4 Purified Protein |产品详情|进口橙子视频旧款采购网




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    KLF4 Purified Protein
    品牌:Abmgood
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    KLF4 Purified Protein

    商品详情 参考文献 相关资料
    Print Version
    Organism Human
    Accession # O43474
    Alias EZF, GKLF
    Protein Type Wild Type
    Protein Sequence HHHHHHRQPPGESDMAVSDALLPSFSTFASGPAGREKTLRQAGAPNNRWREELSHMKRLPPVLPGRPYDLAAATVATDLESGGAGAACGGSNLAPLPRRETEEFNDLLDLDFILSNSLTHPPESVAATVSSSASASSSSSPSSSGPASAPSTCSFTYPIRAGNDPGVAPGGTGGGLLYGRESAPPPTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSAPGSEYGSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGAGPPLSNGHRPAAHDFPLGRQLPSRTTPTLGLEEVLSSRDCHPALPLPPGFHPHPGPNYPSFLPDQMQPQVPPLHYQELMPPGSCMPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHFESGGGGSPGRRRRRRRRR
    Protein Family Belongs to the krueppel C2H2-type zinc-finger protein family.
    Functions   Transcription factor which acts as both an activator and repressor. KLF4 binds the CACCC core sequence. It also binds to multiple sites in the 5'-flanking region of its own gene and can activate its own transcription. KLF4 is required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface.
      KLF4 is one of the four factors in the Yamanaka protocol for iPSC reprogramming. The purified recombinant protein has a 6X His tag at N-terminus for purification and 9X poly-arginine at C-terminus for cell membrane penetration.
    Cell Types Unknown
    Protein locations Nucleus
    Tag 6X His tag at N-terminus and 9X Poly-Arginine at C-terminus
    Form Liquid
    Expression System E.coli
    Type Purified Protein
    Purification Affinity Chromatography
    Quality Control By Western Blot Analysis
    Concentration 250ug/ml
    Storage PBS
    Shipping On dry ice.
    Notes For Research Use Only, not for therapeutic or diagnostic purposes.
    References Induction of pluripotent stem cells from ***** human fibroblasts by defined factors. Takahashi et al. Cell. 2007 Nov 30;131(5):861-72.

    Induction of pluripotent stem cells from mouse embryonic and ***** fibroblast cultures by defined factors. Takahaski and Yamanaka. Cell. 2006 Aug 25;126(4):663-76. Epub 2006 Aug 10.
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