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Oct4 Adenovirus (Human)

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Oct4 Adenovirus (Human)

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	Print Version
Vector	pAdeno
Promoter	CMV
Insert	Oct4
Picture
Organism	Human
Accession #	Q01860
Alias	OCT3, OCT4, OTF3, POU5F1
Protein Type	Wild Type
Protein Family	Belongs to the POU transcription factor family. Class-5 subfamily.
Functions	Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. The product can be used in combination with other iPSC factor for the induction of iPSC reprogramming.
Cell Types	Expressed in developing brain.
Protein locations	Nucleus.
Purification	By Ion-Exchange column.
Quality Control	By sequencing and Western blot analysis of transgene expression in transduced cells. Functional test includes iPSC reprogramming.
Titer	>1x10⁶pfu/mL
Storage	10 mM Tris-HCl, pH 8.0
Shipping	High titer adenoviruses are shipped with dry ice and low titer adenoviruses are shipped with ice packs. For long term storage, it is recommended to store the viruses at -80°C in small aliquots to avoid repeated freeze-thaw cycles.
Notes	For Research Use Only, not for therapeutic or diagnostic purposes.