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Description

  The Adeno-Associated Virus (AAV) offers a uniquely flexible delivery method for the revolutionary gene editing technology, CRISPR Cas9. These small, but powerful viruses open the door to virus-based gene therapy, thanks to a broad range of attractive properties, such as:
 

• Ability to infect both dividing and non-dividing cells
• Low immunogenicity and pathogenicity
• Ability to target a broad range of tissue types
• Long-term expression in non-dividing cells

Our custom design service harnesses the power of CRISPR Cas9 to enable gene editing in a wide range of cell types, both in culture, and animal models. We can supply custom-designed sgRNA-expressing AAV vectors for virtually any application. Our vectors can deliver sgRNAs efficiently into any cells already expressing the Cas9 nuclease, thus targeting the CRISPR Cas9 machinery to trigger gene editing at will.

But that’s not all! For an even simpler experimental setup, we also offer all-in-one CRISPR Cas9 vectors expressing both the compact saCas9 variant, and custom-designed sgRNAs. Simply provide us with a description of your gene editing experiment, and we will deliver viral vectors, as well as pre-packaged viruses, right to your fingertips! Click for custom AAV packaging options and our Cas9-expressing stable cell lines.