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SirtAct, Sirt1 activator

品牌：AG Scientific

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规格：25 mg

货期：

应用：

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CAS:839699-72-8Formula:C20H25N5O2MW:367.46Appearance:OlivegreensolidPurity:98%byTLCNMR(Conforms)

商品详情参考文献相关资料

SirtAct (839699-72-8) is a Sirt1 activator (233% at 10 μM) Suppresses TNFα release from THP-1 cells and stimulates adipogenesis in 3T3L1 cells. SIRT1 stimulation by SirtAct leads to decreased tissue factor mediated thrombogenicity in mice. SirtAct inhibits NFκB activation and reduces inflammatory cytokine production in lamina propria mononuclear cells from IBD patients. Prevents and cures experimental colitis in a mouse model.

Additional Information

Product #	S-3345
CAS #	839699-72-8
Chemical Name	2-Amino-N-cyclopentyl-1-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
Formula	C₂₀H₂₅N₅O₂
MW	367.46
Appearance	Olive green solid
Purity	98% by TLC NMR (Conforms)
Storage Temp	-20°C (des.)