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Romidepsin, HDAC inhibitor

品牌：AG Scientific

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规格：1 mg

货期：

应用：

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CAS:128517-07-7Formula:C24H36N4O6S2MW:540.71Appearance:ColorlesswaxysolidPurity:98%byHPLCNMR(Conforms)

商品详情参考文献相关资料

Romidepsin (2-128517-07-7) is a potent and selective inhibitor of class I histone deacetylases (HDACs), IC₅₀ = 36, 47, 510 and 14,000 nM for HDAC1, 2, 4 and HDAC6, respectively. Induces apoptosis in a variety of cell lines and displays antitumor activity in mouse models. Romidepsin was recently approved for clinical use in T-cell lymphoma.

Additional Information

Synonyms	FK222, FR901228, Depsipeptide
Product #	R-2655
CAS #	128517-07-7
Formula	C₂₄H₃₆N₄O₆S₂
MW	540.71
Appearance	Colorless waxy solid
Purity	98% by HPLC NMR (Conforms)
Solubility	Soluble in DMSO (up to 10 mg/ml).
Storage Temp	-20°