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 AR-A 014418 |产品详情|进口橙子视频旧款采购网




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    订购信息
    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    AR-A 014418
    品牌:AG Scientific
    货号:
    规格:5 mg
    货期:

    CAS:487021-52-3Formula:C12H12N4O4SMW:308.31Appearance:Off-WhiteSolidPurity:98%byTLC

    商品详情 参考文献 相关资料

    Cell-permeable. A selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC= 104 nM). Inhibition is competitive with respect to ATP (K = 38nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (ICvalues are 100M) and over 26 other kinases. Inhibitsamyloid-mediated neurodegeneration in hippocampal slices.

    Additional Information

    Product #A-2498
    CAS #487021-52-3
    Chemical NameN-[(4-METHOXYPHENYL)METHYL]-N'-(5-NITRO-2-THIAZOLYL)UREA
    FormulaC12H12N4O4S
    MW308.31
    AppearanceOff-White Solid
    Purity98% by TLC
    SolubilityDMSO (30 mg/ml)
    Melting Point208-210 °C
    Storage Temp-20°C
    Therapeutic AreaPsychological Disorders
    UseGSK-3 inhibitors useful for the treatment of bipolar disorder and depression.

    Additional Information

    MDL NumberMFCD08277040
    ChemACXX1533647-5
    InChIInChI=1S/C12H12N4O4S/c1-20-9-4-2-8(3-5-9)6-13-11(17)15-12-14-7-10(21-12)16(18)19/h2-5,7H,6H2,1H3,(H2,13,14,15,17)
    SMILESCOc1ccc(cc1)CNC(=O)Nc2ncc(s2)[N+](=O)[O-]
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