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Aprotinin, bovine lung

品牌：AG Scientific

货号：

规格：25 mg

货期：

应用：

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CAS:9087-70-1Formula:C284H432N84O79S7MW:6511.44Appearance:Whitetooff-whitecrystallinepowder.Purity:98%

商品详情参考文献相关资料

Aprotinin is a 58 residue polypeptide serine protease inhibitor which inhibits kallikrein, trypsin, chymotrypsin, plasmin and factor XII an activator of complement. Bovine lungs are the source for Aprotinin and are collected from licensed slaughterhouses in New Zealand. The lungs have passed both pre and post-mortem inspection and are approved for pharmaceutical use by Government Veterinary inspectors in accordance with New Zealand law. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes and dissociating at pH >10 or <3. Effective concentration is equimolar with protease.

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Additional Information

Synonyms	Trypsin Inhibitor, Trypsin-Kallikrein Inhibitor
Product #	A-1420
CAS #	9087-70-1
Formula	C₂₈₄H₄₃₂N₈₄O₇₉S₇
MW	6511.44
Appearance	White to off-white crystalline powder.
Purity	98%
Solubility	Clear, colorless solution. 1% freely soluble in water.
Storage Temp	Store desiccated at +4°C
Use	Aprotinin is a single chain polypeptide (58 amino-acids) crosslinked by three disulfide bridges

Additional Information

MDL Number	MFCD00130541
ChemACX	X1009358-8
InChI	InChI=1S/C22H30N2/c1-3-23(4-2)15-10-16-24(21-13-6-5-7-14-21)22-17-19-11-8-9-12-20(19)18-22/h5-9,11-14,22H,3-4,10,15-18H2,1-2H3
Peptide Sequence	H-ARG-PRO-ASP-PHE-CYS-LEU-GLU-PRO-PRO-TYR-THR-GLY-PRO-CYS-LYS-ALA-ARG-ILE-ILE-ARG-TYR-PHE-TYR-ASN-ALA-LYS-ALA-GLY-LEU-CYS-GLN-THR-PHE-VAL-TYR-GLY-GLY-CYS-ARG-ALA-LYS-ARG-ASN-ASN-PHE-LYS-SER-ALA-GLU-ASP-CYS-MET-ARG-THR-CYS-GLY-GLY-ALA-OH ACETATE

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