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Aminopterin

品牌：AG Scientific

货号：

规格：50 mg

货期：

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CAS:54-62-6Formula:C19H20N8O5MW:440.418Appearance:Solid

商品详情参考文献相关资料

Dihydrofolate reductase inhibitor; blocks nucleotide synthesis

Product #	A-2535
CAS #	54-62-6
Chemical Name	N-[4-[[(2,4-DIAMINO-6-PTERIDINYL)METHYL]AMINO]BENZOYL]-L-GLUTAMIC ACID
Formula	C₁₉ H₂₀ N₈ O₅
MW	440.418
Appearance	Solid
Solubility	Soluble in water (partly), 0.1N NaOH, DMSO, NH4OH 2M (49.00 - 51.00 mg/ml), and ethanol
Melting Point	225 °C
Storage Temp	Room Temp
Therapeutic Area	Oncological Disorders
Use	Aminopterin is a folic acid antagonist. Potent DHFR (dihydrofolate reductase) inhibitor.

MDL Number	MFCD00036692
ChemACX	X1006304-8
InChI	InChI=1S/C19H20N8O5/c20-15-14-16(27-19(21)26-15)23-8-11(24-14)7-22-10-3-1-9(2-4-10)17(30)25-12(18(31)32)5-6-13(28)29/h1-4,8,12,22H,5-7H2,(H,25,30)(H,28,29)(H,31,32)(H4,20,21,23,26,27)
Peptide Sequence	c1cc(ccc1C(=O)NC(CCC(=O)O)C(=O)O)NCc2cnc3c(n2)c(nc(n3)N)N

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