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Isovelleral

品牌：AG Scientific

货号：

规格：1 mg

货期：

应用：

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CAS:37841-91-1Formula:C15H20O2MW:232.4Appearance:Off-WhiteCrystalsPurity:99%

商品详情参考文献相关资料

Isovelleral is an irritant fungal terpenoid that inhibits the TRPV1 (transient receptor potential vanilloid-1) channel. TRPV1 is a Capsaicin receptor that behaves as a non-selective cation channel that is mainly found in the sensory neurons, and specifically detects painful stimuli, low pH and heat.

Research shows that out of twenty unsaturated sesquiterpene dialdehydes tested for cytotoxic and antimicrobial activity, Isovelleral was one of the most potent compounds. The compound has been shown to activate the ion channel, TRPA1, which is associated in the signaling of inflammatory pain. Isovelleral is an inhibitor of VR1 and an activator of ANKTM1.

Additional Information

Product #	I-1034
CAS #	37841-91-1
Chemical Name	(1AS,3AS,6AS,6BR)-5,5,6B-TRIMETHYL-3A,4,5,6,6A,6B-HEXAHYDROCYCLOPROPA[E]INDENE-1A,2(1H)-DICARBALDEHYDE
Formula	C₁₅H₂₀O₂
MW	232.4
Appearance	Off-White Crystals
Purity	99%
Solubility	Soluble in Organic Solvents.
Melting Point	101.85 °C
Storage Temp	Room Temp

Additional Information

MDL Number	MFCD01735881
ChemACX	X1000484-7
InChI	InChI=1S/C15H20O2/c1-13(2)5-10-4-11(7-16)15(9-17)8-14(15,3)12(10)6-13/h4,7,9-10,12H,5-6,8H2,1-3H3/t10-,12+,14-,15-/m1/s1
SMILES	C[C@]12C[C@]1(C(=C[C@H]3[C@@H]2CC(C3)(C)C)C=O)C=O

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