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PD184352

品牌：AG Scientific

货号：

规格：1 mg

货期：

应用：

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CAS:212631-79-3Formula:C17H14CIF2IN2O2MW:478.67Appearance:Whitetooff-whiteSolidPurity:99%byHPLC

商品详情参考文献相关资料

A highly potent ATP-noncompetitive MEK inhibitor. It inhibits MEK with anin vitro IC of 1-1.3 nM. It does not inhibit other kinases. Highly recommended tool to inhibit MKK1 or MKK1 plus MKK5.

Additional Information

Synonyms	CI-1040
Product #	P-1705
CAS #	212631-79-3
Chemical Name	2-(2-CHLORO-4-IODOANILINO)-N-(CYCLOPROPYLMETHOXY)-3,4-DIFLUOROBENZAMIDE
Formula	C₁₇H₁₄CIF₂IN₂O₂
MW	478.67
Appearance	White to off-white Solid
Purity	99% by HPLC
Solubility	DMSO (600 mg/ml)
Melting Point	166-169 °C
Storage Temp	Keep cool and dry, Store at - 20°C
Therapeutic Area	Oncological Disorders
Use	PD184352 a targeted signal transduction inhibitor of MEK use in the treatment of breast and other cancers.

Additional Information

MDL Number	MFCD02683961
ChemACX	X1608406-7
InChI	InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)
SMILES	C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl

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