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EPZ6438

品牌：AG Scientific

货号：

规格：1 mg

货期：

应用：

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CAS:1403254-99-8Formula:C34H44N4O4MW:572.74Appearance:whitepowderPurity:≥99%

商品详情参考文献相关资料

EPZ-6438 is an inhibitor of EZH2, a histone methyltransferase (HMT) responsible for methylation of lysine and arginine residues and controls gene transcription fidelity in cells. EPZ-6438 displays anticancer chemotherapeutic activity in in vivo models by inducing regression of malignant or atypical teratoid rhabdoid tumors containing altered or mutant SWI/SNF ATP-dependent chromatin remodelers.

Additional Information

Synonyms	E7438, Tazemetostat
Product #	E-2511
CAS #	1403254-99-8
Chemical Name	N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl(oxan-4-yl)amino]-2-methyl-5-[4-(morpholin-4-ylmethyl)phenyl]benzamide
Formula	C₃₄H₄₄N₄O₄
MW	572.74
Appearance	white powder
Purity	≥99%
Solubility	In DMSO
Storage Temp	-20°C