MF-438, SCD1 inhibitor |产品详情|进口橙子视频旧款采购网

您好，欢迎来到橙子视频app安卓下载生物网站！请登录注册

我的订单 | 联系橙子视频app安卓下载 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA91橙子视频、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口橙子视频旧款、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于橙子视频app安卓下载

所在位置：首页 > 产品中心 > AGScientific > AGScientific产品

订购信息

上海橙子视频app安卓下载生物科技公司

Tel:400-968-7988 021-33779008

MF-438, SCD1 inhibitor

品牌：AG Scientific

货号：

规格：25 mg

货期：

应用：

咨询客服

立即购买加入购物车

CAS:921605-87-0Formula:C19H18F3N5OSMW:421.44Appearance:Off-whitesolidPurity:98%byHPLCNMR(Confirms)

商品详情参考文献相关资料

MF-438 (921605-87-0) is a potent inhibitor of stearoyl-CoA desaturase 1 (SCD1) - IC₅₀= 2.3 nM. MF-438 was potent in an in vivo mouse liver PD assay (ED₅₀ between 1 and mg/kg). Cancer initiating cells (CSC-like) were shown to much more sensitive to MF-438 inhibition of SCD1 than progenitor and terminally differentiated cancer cells in a lung cancer model. MF-438 showed good oral bioavailability and metabolic stability making it an excellent tool for studying the effects of SCD1 in various disease models.

Additional Information

Product #	M-3329
CAS #	921605-87-0
Chemical Name	2-Methyl-5-(6-(4-(2-trifluoromethyl)phenoxy)piperidin-3-yl)-1,3,4-thiadiazole
Formula	C₁₉H₁₈F₃N₅O_S
MW	421.44
Appearance	Off-white solid
Purity	98% by HPLC NMR (Confirms)
Solubility	Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 2 mg/ml with warming).
Storage Temp	-20°