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Phenylhexyl Isothiocyanate |产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    Phenylhexyl Isothiocyanate
    品牌:AG Scientific
    货号:
    规格:25 mg
    货期:

    CAS:133920-06-6Formula:C13H17NSMW:219.35Appearance:ClearcolorlessliquidPurity:≥98%

    商品详情 参考文献 相关资料

    Isothiocyanates are compounds typically found in plants of the Brassicaceae family, including broccoli, cabbage, and radish. Isothiocyanates are best known for their antioxidative, anticancer chemotherapeutic, chemopreventive, anti-angiogenic, and antibiotic properties. In vitro, phenhexyl isothiocyanate (PHITC) increases caspase 3 activity and cleavage of poly(ADP)-ribose polymerase (PARP), inducing caspase-mediated apoptosis in cellular models. This compound decreases oxidation of carcinogen NNK and increases activity of NADPH:quinone oxidoreductase and glutathione S-transferase in vitro and in vivo. PHITC inhibits histone deacetylase (HDAC) activity, IL-6 receptor production, and VEGF expression; it also induces mitochondrial membrane depolarization and apoptosis in myeloma cells. In leukemia cells, PHITC inhibits expression of cyclin and increases expression of cyclin dependent kinase (CDK) inhibitors, inducing apoptosis and inhibiting growth of xenografts of these cells in animals.

    Additional Information

    Synonyms6-Phenylhexyl isothiocyanate; PHITC
    Product #P-2951
    CAS #133920-06-6
    Chemical Name6-isothiocyanatohexylbenzene
    FormulaC13H17NS
    MW219.35
    AppearanceClear colorless liquid
    Purity≥98%
    SolubilitySoluble in oraganic solvents.
    Storage Temp-20°C

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