KT-5823| CAS [126643-37-6] | Potent, selective inhibitor of PKG| induces apopto |产品详情|进口橙子视频旧款采购网

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KT-5823| CAS [126643-37-6] | Potent, selective inhibitor of PKG| induces apopto

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KT-5823| CAS [126643-37-6] | Potent, selective inhibitor of PKG| induces apopto

品牌：AG Scientific

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规格：100 ug

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CAS:126643-37-6Formula:C29H25N3O5MW:495.5Appearance:WhiteSolidPurity:99.06%

商品详情参考文献相关资料

KT5823 a staurosporine-related protein kinase inhibitor, is a K-252 compound. KT5823, is an in vitro inhibitor of cGK, has also been used in numerous studies with intact cells to implicate or rule out the involvement of this protein kinase in a given cellular response. KT5823 Inhibits cGMP-dependent Protein Kinase Activity in Vitro but not in Intact Human Platelets and Rat Mesangial Cells.

KT5823, has been shown to increase thyroid - stimulating hormone-induced Na⁺/I^-symporter expression, and thus iodide uptake, in thyroid cells. KT5823- mediated effects on Na⁺/I^-symporter activity and glycosylation are also observed in breast cancer cells as well as human embryonic kidney cells expressing exogenous NIS.

Additional Information

Product #	K-1040
CAS #	126643-37-6
Formula	C₂₉H₂₅N₃O₅
MW	495.5
Appearance	White Solid
Purity	99.06%
Solubility	Soluble in DMSO @ 25mg/ml, DMF @ 20mg/ml, EtOAc @ 5 mg/ml.
Melting Point	272 - 276°C
Storage Temp	Keep cool and dry at +4°C