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Pyrintegrin---CellSurvivalEnhancer M60028-2s|产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    Pyrintegrin---CellSurvivalEnhancer
    品牌:Xcessbio
    货号:M60028-2s
    规格:2 mg solid
    货期:

    Pyrintegrin---CellSurvivalEnhancer

    商品详情 参考文献 相关资料
    Product Information
    Molecular Weight: 451.54
    Formula: C23H25N5O3S
    Purity: ≥98%
    CAS#: 1228445-38-2
    Solubility: DMSO up to 100 mM
    Chemical Name: N-(cyclopropylmethyl)-4-((4-(6-hydroxy-3,4-dihydroquinolin-1(2H)-yl)pyrimidin-2-yl)amino)benzenesulfonamide
    Storage: Powder: 4oC 1 year. DMSO: 4oC 3 month; -20oC 1 year.

    Biological Activity:

    Pyrintegrin is a cell-permeable small molecule that promotes human embryonic stem cell (hESC) survival by > 30-fold. Pyrintegrin can enhance cell-ECM adhesion-mediated integrin signaling. It can also stabilize the cell surface protein E-cadherin after cell dissociation.


    How to Use:

    • In vitro: Pyrintegrin was used at 3-5 µM concentration in cell culture.
    • In vivo: n/a


    Reference:

    1. 1. Xu Y, et al. Revealing a core signaling regulatory mechanism for pleuripotent stem cell survival and self-renewal by small molecules. (2010) PNAS 107(18): 8129-8134.


         

    Products are for research use only. Not for human use.

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