PRMT1-2e,ProteinArginineMethyltransferase1(PRMT1)Inhibitor M60181-5s|产品详情|进口橙子视频旧款采购网

您好，欢迎来到橙子视频app安卓下载生物网站！请登录注册

我的订单 | 联系橙子视频app安卓下载 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA91橙子视频、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口橙子视频旧款、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于橙子视频app安卓下载

所在位置：首页 > 产品中心 > Xcessbio > Xcessbio产品

PRMT1-2e,ProteinArginineMethyltransferase1(PRMT1)Inhibitor

订购信息

上海橙子视频app安卓下载生物科技公司

Tel:400-968-7988 021-33779008

PRMT1-2e,ProteinArginineMethyltransferase1(PRMT1)Inhibitor

品牌：Xcessbio

货号：M60181-5s

规格：5 mg solid

货期：

应用：

咨询客服

立即购买加入购物车

PRMT1-2e,ProteinArginineMethyltransferase1(PRMT1)Inhibitor

商品详情参考文献相关资料

Product Information

Molecular Weight:	401.26
Formula:	C₁₆H₁₄Cl₂N₂O₄S
Purity:	≥98%
CAS#:	17328-16-4
Solubility:	DMSO up to 50 mM
Chemical Name:	N,N'-(sulfonylbis(4,1-phenylene))bis(2-chloroacetamide)
Storage:	Powder: 4^oC 1 year. DMSO: 4^oC 3 month; -20^oC 1 year.

Biological Activity:

PRMT1-2e is a potent, specific and cell permeable inhibitor of protein arginine methyltransferase 1 (PRMT1) with an IC₅₀ ~1.5 μM. It has no activity against CARM1 and Set7/9 methyltransferases. It inhibits growth of MCF7a breast cancer cells (IC₅₀ ~1.97 μM) and LNCaP prostate cancer cells (IC₅₀ ~4.49 μM). It can attenuate androgen-induced gene expression in LNCaP cells.

How to Use:

In vitro: PRMT1-2e was used at 10 µM in vitro.
In vivo: n/a

Reference:

1. Bissinger EM, et al. Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1. (2011) Bioorg Med Chem. 19(12):3717-31.

Products are for research use only. Not for human use.

热销产品