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BAZ2-ICR,BAZ2BromodomainInhibitor M60226-2s|产品详情|进口橙子视频旧款采购网




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    上海橙子视频app安卓下载生物科技公司
    Tel:400-968-7988    021-33779008
    BAZ2-ICR,BAZ2BromodomainInhibitor
    品牌：Xcessbio
    货号：M60226-2s
    规格：2 mg solid
    货期：

    BAZ2-ICR,BAZ2BromodomainInhibitor
    商品详情 参考文献 相关资料
    Product Information
    Molecular Weight: 357.41
    Formula: C20H19N7
    Purity: ≥98%
    CAS#: n/a
    Solubility: DMSO up to 100 mM
    Chemical Name: 4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile
    Storage: Powder: 4oC 1 year. DMSO: 4oC 3 month; -20oC 1 year.

    Biological Activity:

    BAZ2-ICR is a potent and selective BAZ2 bromodomain inhibitor with Kd values of 109 and 170 nM for BAZ2A and BAZ2B, respectively. It exhibits 15-fold selectivity for the BAZ2 bromodomain over the CERC2 bromodomain and >100-fold selectivity over a range of other bromodomains. It shows accelerated FRAP recovery at 1 µM in the BAZ2A FRAP assay.

    How to Use:

    In vitro:  BAZ2-ICR was used at 1-10 µM final concentration in various in vitro assays.

    In vivo: n/a

    Reference:

    • 1.      http://www.thesgc.org/chemical-probe/BAZ2-ICR

     


    Products are for research use only. Not for human use. 

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