气道平滑肌是维持气道张力的根本。它存在于气管、支气管树直至终末支气管。其特异的*微结构特点和调节机制是实现气管正常生理功能的基础。有证据表明气管平滑肌在肺的发育过程以及诸如**病、慢性****和肺气肿等疾病状态下经历着显著的表型变化。另外，气道平滑肌通过分泌细胞因子和趋化因子等促炎介质，发挥免疫调节功能。培养的气管平滑肌细胞能表达三种P21活化的激酶（PAK）的同型异构体和PAK1，并通过P38 mapk信号途径参与气管平滑肌细胞的迁移。气道平滑肌细胞增殖已成为人们关注的焦点，因为在**病人中，此细胞是气道壁重塑反应中数量上的重要组分，并被认为是新型抗**病药物的作用目标。
人气管平滑肌细胞提取于人气管组织，二代冻存。每管含有细胞数>5×105 cells/ml，此细胞通过对alpha-SMA和Desmin免疫荧光染色验证，经测试不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌。细胞可以达到15倍增。? ?
推荐培养基：平滑肌细胞培养基 (SMCM, Cat. #1101)
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货号
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3410
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产地
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美国
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缩写
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HTSMC
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规格
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5 x 10^5 /1ml
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用途
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科研
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储存
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液氮
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运输
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干冰
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