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Anti-FANCG (Phospho-Ser383) Antibody |产品详情|进口橙子视频旧款采购网




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    Anti-FANCG (Phospho-Ser383) Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-FANCG (Phospho-Ser383) Antibody

    商品详情 参考文献 相关资料
    Name: Anti-FANCG (Phospho-Ser383) Antibody
    See all FANCG primary antibodies
    Description: Rabbit polyclonal antibody to FANCG (Phospho-Ser383)
    Specificity: The antibody detects endogenous levels of FANCG only when phosphorylated at serine 383.
    Applications: WB
    Dilutions: Western blotting: 1:500~1:3000
    Reactivity: Human
    Immunogen: Peptide sequence around phosphorylation site of serine 383 (R-F-S(p)-P-P) derived from Human FANCG.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
    Concentration: 1.0mg / ml
    Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    Storage: Store at -20˚C
    Function: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
    Tissue Specificity: Highly expressed in testis and thymus. Found in lymphoblasts.
    Involvement in Disease: Fanconi anemia complementation group G: A disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair.
    Cellular locations: Nucleus. Cytoplasm.

    The major form is nuclear. The minor form is cytoplasmic.
    Database Links:
  • Entrez Gene: 2189 Human
  • Omim: 602956 Human
  • SwissProt: O15287 Human
  • Unigene: 591084 Human
  • Synonyms:
  • DNA repair protein XRCC9 Antibody
  • FAG Antibody
  • FANCG Antibody
  • FANCG_HUMAN Antibody
  • Fanconi anaemia complementation group G Antibody
  • Fanconi anemia group G protein Antibody
  • Protein FACG Antibody
  • X ray repair, complementing defective, in Chinese hamster cells 9 Antibody
  • X-ray repair, complementing defective, in Chinese hamster, 9 Antibody
  • XRCC9 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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