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Anti-Emerin Antibody

品牌：Antibodies

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规格：100µl

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Anti-Emerin Antibody

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Name:	Anti-Emerin Antibody See all Emerin primary antibodies
Description:	Rabbit polyclonal antibody to Emerin
Applications:	E, WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Raised against a 19 amino acid peptide from near the amino terminus of human Emerin.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity chromatography purified via peptide column
Formulation:	Supplied in PBS containing 0.02% sodium azide.
Storage:	Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Function:	Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. Required for proper localization of non-farnesylated prelamin-A/C (By similarity).
Cellular locations:	Nucleus inner membrane. Nucleus outer membrane. Colocalized with BANF1 at the central region of the assembling nuclear rim, near spindle-attachment sites. The accumulation of different intermediates of prelamin-A/C (non-farnesylated or carboxymethylated farnesylated prelamin-A/C) in fibroblasts modify its localization in the nucleus (By similarity).
Database Links:	Entrez Gene: 2010?Human Entrez Gene: 13726?Mouse Entrez Gene: 25437?Rat Omim: 300384?Human SwissProt: P50402?Human SwissProt: O08579?Mouse SwissProt: Q63190?Rat Unigene: 522823?Human Unigene: 18892?Mouse Unigene: 10968?Rat
Synonyms:	EDMD Antibody Emd Antibody EMD_HUMAN Antibody Emerin Antibody Emery Dreifuss muscular dystrophy Antibody STA Antibody
Information:	Target information shown above is from the UniProt Consortium.