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Anti-DLC1 Antibody

品牌：Antibodies

货号：

规格：50µl

货期：

应用：

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Anti-DLC1 Antibody

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Overview

Name:	Anti-DLC1 Antibody See all DLC1 primary antibodies
Description:	Rabbit polyclonal antibody to DLC1.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human DLC1.
Protein Length:	1528(463)
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
Tissue Specificity:	Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus.
Cellular locations:	Cytoplasm. Cell junction > Focal adhesion. Membrane. Colocalizes with EF1A1 at actin-rich regions in the cell periphery.
Database Links:	Entrez Gene: 10395?Human Entrez Gene: 50768?Mouse Entrez Gene: 58834?Rat Omim: 604258?Human SwissProt: Q96QB1?Human SwissProt: Q9R0Z9?Mouse SwissProt: Q63744?Rat Unigene: 134296?Human Unigene: 210875?Mouse Unigene: 224563?Rat
Synonyms:	ARHGAP 7 Antibody ARHGAP7 Antibody Deleted in liver cancer 1 Antibody Deleted in liver cancer 1 protein Antibody DLC 1 Antibody Dlc-1 Antibody DLC1 Antibody DLC1 Rho GTPase activating protein Antibody FLJ21120 Antibody HP Antibody HP protein Antibody KIAA1723 Antibody p122 RhoGAP Antibody RHG07_HUMAN Antibody Rho GTPase activating protein 7 Antibody Rho GTPase-activating protein 7 Antibody Rho type GTPase activating protein 7 Antibody Rho-type GTPase-activating protein 7 Antibody StAR related lipid transfer (START) domain containing 12 Antibody StAR related lipid transfer protein 12 Antibody StAR-related lipid transfer protein 12 Antibody STARD 12 Antibody StARD12 Antibody START domain containing protein 12 Antibody START domain-containing protein 12 Antibody
Information:	Target information shown above is from the UniProt Consortium.