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Anti-CYP46A1 Antibody

品牌：Antibodies

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规格：50µl

货期：

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Anti-CYP46A1 Antibody

商品详情参考文献相关资料

Name:	Anti-CYP46A1 Antibody See all CYP46A1 primary antibodies
Description:	Rabbit polyclonal antibody to CYP46A1.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:100.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human CYP46A1.
Protein Length:	500
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. Has also activity with xenobiotic compounds, such as clotrimazole.
Tissue Specificity:	Expressed in brain. The mRNA was broadly distributed with higher levels in gray matter zones and lower levels in regions rich in white matter. Not detected in fetal sample but its expression increases linearly with age.
Sequence Similarities:	Belongs to the cytochrome P450 family.
Cellular locations:	Endoplasmic reticulum membrane. Microsome membrane.