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Anti-CXXC5 Antibody

品牌：Antibodies

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规格：100µl

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Anti-CXXC5 Antibody

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Name:	Anti-CXXC5 Antibody See all CXXC5 primary antibodies
Description:	Rabbit polyclonal antibody to CXXC5
Specificity:	The antibody detects endogenous levels of total CXXC5 protein.
Applications:	IHC
Reactivity:	Human, Mouse
Immunogen:	Full length fusion protein
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	0.8mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen) (PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (PubMed:23303788).
Cellular locations:	Nucleus. Cytoplasm. Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane.
Database Links:	Entrez Gene: 51523?Human Entrez Gene: 67393?Mouse Omim: 612752?Human SwissProt: Q7LFL8?Human SwissProt: Q91WA4?Mouse Unigene: 189119?Human Unigene: 94560?Mouse
Synonyms:	CF5 Antibody CXXC finger 5 protein Antibody CXXC finger protein 5 Antibody CXXC-type zinc finger protein 5 Antibody CXXC5 Antibody CXXC5_HUMAN Antibody HSPC195 Antibody Putative MAPK-activating protein PM08 Antibody Putative NF-kappa-B-activating protein 102 Antibody retinoid-inducible nuclear factor Antibody RINF Antibody TCCCIA00297 Antibody WID Antibody WT1-induced Inhibitor of Dishevelled Antibody
Information:	Target information shown above is from the UniProt Consortium.