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Anti-CHRNA2 Antibody

品牌：Antibodies

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规格：100µl

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Anti-CHRNA2 Antibody

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Name:	Anti-CHRNA2 Antibody See all CHRNA2 primary antibodies
Description:	Rabbit polyclonal antibody to CHRNA2
Specificity:	The antibody detects endogenous levels of total CHRNA2 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to a region derived from internal residues of human cholinergic receptor, nicotinic, alpha 2 (neuronal)
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.9mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Involvement in Disease:	Epilepsy, nocturnal frontal lobe, 4: An autosomal dominant focal epilepsy characterized by nocturnal seizures associated with fear sensation, tongue movements, and nocturnal wandering, closely resembling nightmares and sleep walking.
Sequence Similarities:	Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-2/CHRNA2 sub-subfamily.
Cellular locations:	Cell junction > Synapse > Postsynaptic cell membrane. Cell membrane.
Database Links:	Entrez Gene: 1135?Human Omim: 118502?Human SwissProt: Q15822?Human Unigene: 57718?Human
Synonyms:	ACHA2_HUMAN Antibody AChR Antibody Cholinergic receptor nicotinic alpha 2 Antibody Chrna2 Antibody Neuronal acetylcholine receptor protein subunit alpha 2 Antibody Neuronal acetylcholine receptor subunit alpha-2 Antibody Nicotinic Acetylcholine Receptor alpha 2 Antibody
Information:	Target information shown above is from the UniProt Consortium.