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 Anti-Caspase-1 p20 (D210) Antibody |产品详情|进口橙子视频旧款采购网




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    Anti-Caspase-1 p20 (D210) Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-Caspase-1 p20 (D210) Antibody

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    Name: Anti-Caspase-1 p20 (D210) Antibody
    See all Caspase-1 p20 primary antibodies
    Description: Rabbit polyclonal antibody to Caspase-1 p20 (D210)
    Specificity: Caspase-1 p20 (D210) pAb detects endogenous levels of pro-caspase-1 and the caspase-1 p20 subunit. The antibody is expected to detect alpha, beta, gamma and delta isoforms.
    Applications: WB, IHC
    Reactivity: Human, Mouse, Rat
    Immunogen: Synthetic peptide, corresponding to amino acids 180-230 of Human Caspase-1 p20.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Molecular Weight: ~ 20, 30-45, 50 kDa
    Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
    Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
    Function: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
    Tissue Specificity: Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.
    Sequence Similarities: Belongs to the peptidase C14A family.
    Post-Translational Modification: The two subunits are derived from the precursor sequence by an autocatalytic mechanism.
    Cellular locations: Cytoplasm.
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