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Anti-CASP8AP2 Antibody

品牌：Antibodies

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规格：100µl

货期：

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Anti-CASP8AP2 Antibody

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Name:	Anti-CASP8AP2 Antibody See all CASP8AP2 primary antibodies
Description:	Rabbit polyclonal antibody to CASP8AP2
Specificity:	The antibody detects endogenous levels of total CASP8AP2 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to a region derived from internal residues of human caspase 8 associated protein 2
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation. Involved in TNF-alpha-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis. Required for histone gene transcription and progression through S phase.
Cellular locations:	Cytoplasm. Nucleus. Nucleus > PML body. Mitochondrion. Exported from the nucleus to the mitochondria upon FAS activation.
Database Links:	Entrez Gene: 9994?Human Omim: 606880?Human SwissProt: Q9UKL3?Human Unigene: 558218?Human
Synonyms:	AA387232 Antibody C8AP2_HUMAN Antibody CASP 8 associated protein 2 Antibody CASP8 associated protein 2 Antibody CASP8-associated protein 2 Antibody CASP8AP2 Antibody Caspase 8 associated protein 2 Antibody CED 4 Antibody CED4 Antibody D4Ertd659e Antibody FLASH Antibody FLASH homolog Antibody FLASH homolog RIP 25 Antibody FLASH homolog RIP25 Antibody FLICE associated huge Antibody FLICE associated huge protein Antibody FLICE-associated huge protein Antibody FLJ11208 Antibody KIAA1315 Antibody mKIAA1315 Antibody OTTMUSP00000005125 Antibody RIP 25 Antibody RIP25 Antibody RP23-69G24.1 Antibody
Information:	Target information shown above is from the UniProt Consortium.