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Anti-CAMK1D Antibody

品牌：Antibodies

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规格：100µl

货期：

应用：

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Anti-CAMK1D Antibody

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Overview

Name:	Anti-CAMK1D Antibody See all CAMK1D primary antibodies
Description:	Rabbit polyclonal antibody to CAMK1D
Specificity:	The antibody detects endogenous levels of total CAMK1D protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to a region derived from internal residues of human calcium / calmodulin-dependent protein kinase ID
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	2.1mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta.
Tissue Specificity:	Widely expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.
Sequence Similarities:	Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Cellular locations:	Cytoplasm. Nucleus. Predominantly cytoplasmic. Nuclear localization increases upon activation by KCl treatment in hippocampal neurons.
Database Links:	Entrez Gene: 57118?Human Omim: 607957?Human SwissProt: Q8IU85?Human Unigene: 659517?Human
Synonyms:	A630059D12Rik Antibody Calcium/calmodulin dependent protein kinase ID Antibody Calcium/calmodulin dependent protein kinase type 1D Antibody Calcium/calmodulin-dependent protein kinase I-delta Antibody Calcium/calmodulin-dependent protein kinase type 1D Antibody CaM K1 Antibody CaM KI delta Antibody CaM kinase I delta Antibody CaM kinase ID Antibody CaM-KI delta Antibody CAMK 1D Antibody CAMK1D Antibody CaMKI delta Antibody CamKI like protein kinase Antibody CamKI-like protein kinase Antibody CaMKID Antibody CKLiK Antibody E030025C11Rik Antibody KCC1D_HUMAN Antibody OTTHUMP00000019119 Antibody OTTHUMP00000019120 Antibody OTTHUMP00000045030 Antibody RP11 462F15.1 Antibody
Information:	Target information shown above is from the UniProt Consortium.