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Anti-CACNA1 Antibody

品牌：Antibodies

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规格：100µl

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Anti-CACNA1 Antibody

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Name:	Anti-CACNA1 Antibody See all CACNA1 primary antibodies
Description:	Rabbit polyclonal antibody to CACNA1
Specificity:	The antibody detects endogenous levels of total CACNA1 protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to a region derived from internal residues of human calcium channel, voltage-dependent, L type, alpha 1D subunit
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	2mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling (By similarity).
Tissue Specificity:	Isoform 1 is expressed in skeletal muscle. Isoform 2 is expressed in the central nervous system. Isoform 2, isoform 4 and isoform 5 are expressed in neuroblastoma cells. Isoform 3, isoform 4 and isoform 5 are expressed in the aorta.
Sequence Similarities:	Belongs to the calcium channel subunit alpha-2/delta family.
Post-Translational Modification:	Proteolytically processed into subunits alpha-2-1 and delta-1 that are disulfide-linked.
Cellular locations:	Membrane.