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 Anti-Bone morphogenetic protein 2 Antibody |产品详情|进口橙子视频旧款采购网




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    Anti-Bone morphogenetic protein 2 Antibody
    品牌:Antibodies
    货号:
    规格:100µl
    货期:

    Anti-Bone morphogenetic protein 2 Antibody

    商品详情 参考文献 相关资料
    Name: Anti-Bone morphogenetic protein 2 Antibody
    See all Bone morphogenetic protein 2 primary antibodies
    Description: Rabbit polyclonal antibody to Bone morphogenetic protein 2
    Specificity: The antibody detects endogenous level of total Bone morphogenetic protein 2 polyclonal antibody.
    Applications: IHC
    Reactivity: Human
    Immunogen: Recombinant human Bone morphogenetic protein 2 protein
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
    Concentration: 1.0mg / mL
    Formulation: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
    Storage: Store at -20?C
    Function: Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).
    Tissue Specificity: Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
    Sequence Similarities: Belongs to the TGF-beta family.
    Cellular locations: Secreted.
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