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Anti-WNT4 Antibody |产品详情|进口橙子视频旧款采购网




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    Anti-WNT4 Antibody
    品牌:Antibodies
    货号:
    规格:100µl
    货期:

    Anti-WNT4 Antibody

    商品详情 参考文献 相关资料
    Name: Anti-WNT4 Antibody
    See all WNT4 primary antibodies
    Description: Mouse monoclonal antibody to WNT4.
    Applications: WB, IHC, IF, IP
    Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:50 - 1:100, IP: 1:20 - 1:50.
    Reactivity: Human, Mouse, Rat
    Immunogen: A synthetic peptide of human WNT4.
    Host: Mouse
    Clonality: Monoclonal
    Isotype: IgG
    Conjugate: Unconjugated
    Purification: Affinity purification.
    Product Form: Liquid
    Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
    Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). Overexpression may be associated with abnormal proliferation in human breast tissue.
    Involvement in Disease: 46,XX sex reversal with dysgenesis of kidneys, adrenals, and lungs: A disease characterized by the association of female-to-male sex reversal with dysgenesis of kidneys, adrenals, and lungs.

    Mullerian aplasia and hyperandrogenism: A disorder of sex development. Affected females manifest dysgenesis of Mullerian duct derivatives absent or rudimentary uterus and vagina, functional ovaries, primary amenorrhea, hyperandrogenism and hirsutism.
    Sequence Similarities: Belongs to the Wnt family.
    Post-Translational Modification: Palmitoleylation is required for efficient binding to frizzled receptors. Depalmitoleylation leads to Wnt signaling pathway inhibition.
    Cellular locations: Secreted > Extracellular space > Extracellular matrix.
    Database Links:
  • Entrez Gene: 54361?Human
  • Entrez Gene: 22417?Mouse
  • Entrez Gene: 84426?Rat
  • Omim: 603490?Human
  • SwissProt: P56705?Human
  • SwissProt: P22724?Mouse
  • SwissProt: Q9QXQ5?Rat
  • Unigene: 25766?Human
  • Unigene: 611722?Human
  • Unigene: 20355?Mouse
  • Unigene: 34782?Rat
  • Synonyms:
  • MGC123964 Antibody
  • Protein Wnt-4 Antibody
  • RP23-246F18.1 Antibody
  • SERKAL Antibody
  • Wingless type MMTV integration site family member 4 precursor Antibody
  • WNT 4 Antibody
  • WNT 4 protein precursor Antibody
  • Wnt4 Antibody
  • WNT4_HUMAN Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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